Zabbix VS Zenoss

Zenoss was my favourite network monitoring tool, But it is Zabbix now. The conclusion was made after comparing Zenoss 3.0.3 to Zabbix 1.8.3 in Lab environment.

Features	Zenoss	Zabbix
Server	Zope application server (in Phyton)	Server Daemon (Written in C)
Frontend	Phyton	PHP
Backend	Mysql	MySQL, PostgreSQL, SQLite or Oracle
Client	None	Linux,Window,BSD,AIX,HP-UX,Solaris
Monitoring methods	SNMP/SSH/External command	SNMP/Agent/SSH/External command
Graphing	Supported	Supported
Cost	Zenoss Core and community contributed zenpacks are free	All features are free
Others	Latest package in RPMS/DEB, very easy to install Heavy weight due to Phyton and Zope, requires higher hardware specs	Latest package has to be compiled from source Light weight, the Server daemon has very small footprint, the other components are just web server(e.g. Apache) and DB server.

As shown in the above table, Zabbix has more features than Zenoss's  

Zenoss Strength

Better looking GUI Zabbix's  PHP can't beat Zenoss's Phyton
Better support for SNMP
Zenoss has built-in snmp template for monitoring servers, Server auto discovery is smooth
Because Zabbix is more agent focused, Zabbix doesn't include snmp template  for monitoring servers (at least in 1.8.3), You have to create your own.
Lots of community contributed zenpacks
Better support for agent-less type of  Windows  Servers
Actually Zabbix has better support for  Windows servers, if you don't mind installing monitoring agent.
For agent-less monitoring, Zenoss is easier than Zabbix. Because Zenoss has  zenpacks for Windows.
Zabbix users have to write their own WMI scripts using  WMI tool, which can be downloaded and complied from http://dev.zenoss.org/svn/trunk/inst/externallibs/
or use SNMP Provider to link SNMP to WMI

Zabbix Strength

Graphing
You don't need to create graph definition for a single data source, the graph can be dynamically generated on demand. For multi-data source graph (e.g. SYS CPU/USR CPU in one graph) , the graph definition is easier than Zenoss (changing display order is just a matter of clicking up/down button.
Alarm expression It seems Zenoss only supports alarm value ranging  from min to max in numeric values.
Zabbix supports dozens of expressions: avg,min,max,last,diff,regexp …
for example you can use regexp ('ERROR') to check if the response contains string “ERROR”
Web application monitoring
Zabbix supports  complex scenarios consisting of many steps (HTTP requests) .e.g login, execute some tasks, logout 
Unique Agent checks Search Windows Event log for a string: eventlog[logtype,<pattern>,<severity>,<source>,<eventid>,<maxlines>]   
Search any text file for a string:
log[file,<pattern>,<encoding>,<maxlines>]
Check if a file has been modified:
vfs.file.cksum [file]:
Zabbix Proxy
Zabbix Proxy is a process which collects performance and availability data from one or more monitored devices and sends the information to a Zabbix Server.  It is very useful for monitoring device which can't be reached by  Zabbix Server
---Update Zabbix 2.0 Low Level Discovery
Zabbix 2.0 has new feature called Low Level Discovery,It can do SNMP dynamic discovery and any customized application discovery based on JSON format. In order to monitor an item of a script output, other monitoring system  I know of requires item name has to be typed in manually through UI, but Zabbix can discover the item automatically, if there dozens of items to be monitored, huge  amount of maintenance effort will be saved. check out this example. http://honglus.blogspot.com.au/2013/01/zabbix-monitor-customized-applications.html